Diseases, Disorders information

Burton’s Anatomy of Melancholia (1621)

1. “A kind of dotage without a fever, having for his ordinary companions fear and sadness, without any apparent occasion”
2. Sadness among symptoms but not the defining characteristic.
3. 3 Subtypes: Primary: Generalized: Hypochondriacal
4. Clinico-anatomical (19 th century)

1. Associated overt signs of illness with anatomical lesions. Failure to identify lesions in patients with mental illness had two major consequences;

1. The concept of neurosis gradually changed from a label implying tissue pathology to a psychodynamic formulation.

2. In the absence of etiological classification the basis of nosology was descriptive classification

1. Under the descriptive system separate clusters of mental functions could become diseased separately.

1. Intellectual
2. Emotional

3. Volitional

5. Falret 1854
1. Memoire sur la Folie Circulaire
1. Described cyclical course of mood including “folie a double forme”