Oral isotretinoin. Acne Development of the modern concept primary mood disorders
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Overview of Mood Disorders
Introduction
1. Mood disorders occupy a place of special importance in the clinical practice and nosology of psychiatry.

1. Mood disorders are common

1. Most epidemiological studies find the lifetime prevalence of mania be about one percent. When bipolar type II, cyclothymia and other forms of bipolar illness are included the prevalence increases to between 2 and 3 %.
2. Unipolar Depression lifetime prevalence Male12%, Female 25%

3. High rate of suicide

1. 15% Lifetime risk of suicide
2. Risk is 30 times greater than general population
3. 50% of all suicides are committed by depressed patients
4. The most common reason for psychiatric hospitalization
1. At any time 2-3% of the population (USA and Europe) are seriously -impaired are hospitalized due to affective illness.
5. The annual direct cost of mood disorders in the USA = $16 billion
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2. Mood disorder is often hard to recognize

1. encompass patients ranging from mildly ill to severely disabled
2. the value of patient self report is excellent for ruling out depression
3. the value of patient self report is poor for ruling out mania
4. Reporting is heavily influenced by current mood state

3. The course of mood disorders can be greatly influenced

1. Cycle promoting Treatments
2. Mood Stabilizing treatments
3. Substance abuse
4. Life style

4. Subtpying Mood disorders can guide treatment decisions because the different disorders have prognostic significance and
2. This presentation will focus on the development of the mood disorder concept , current diagnostic criteria and the clinical features of bipolar illnesses.

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